Multi-Lead Multi-Electrode Management System

TECHNOLOGY OPPORTUNITY

Florida International University (FIU) is seeking companies interested in commercializing a Multi-lead Multi-electrode Management System that significantly improves the way multiple leads or connecting elements with multiple electrode contacts could be deployed to either stimulate or record from several muscles or nerves that span over a large two-dimensional area. Current technology allows a single lead to contain multiple electrode contacts along the longitudinal axis of the lead at predetermined distances. Such leads are used to stimulate excitable neural tissue that is only in the vicinity of the lead. Researchers at FIU have developed a system to deploy multiple leads carrying one or more multiple electrodes such that each electrode is separable. This method eliminates several practical hurdles in the management of multiple electrode leads for development of therapies that require pacing, sensing, or both, of muscles or nerves innervating such muscles. This novel arrangement of packaging and management of multiple leads, each one carrying multiple electrodes, allows for the deployment of a multitude of separable electrodes to nerves or muscle tissues that are spatially distributed over a large two-dimensional area such as gastric tissue and respiratory muscles.

This multi-lead multi-electrode management system was initially developed for recording peripheral nerve activity from multiple nerves at multiple sites using longitudinal intrafascicular electrodes in what is called a Distributed Intrafascicular Multi-Electrode (DIME) system. In a DIME system, there are multiple leads with multiple intrafascicular electrodes targeting multiple nerves. With a packaging that prevents entanglement of the individual leads and electrode wires during implantation, the resulting system is one which can more easily allow routing and distributed deployment of multiple electrodes over a greater area thereby allowing stimulation of multiple nerves at multiple sites.

APPLICATIONS

A multi-lead multi-electrode system is able to deploy multiple separable electrodes to various distant contact sites, such as nerve or muscle tissues that are spatially distributed over a large area. Some possible uses include sensing or pacing or simultaneous sensing and pacing of affected muscles or nerves for treating gastric disorders, respiratory insufficiency and for bidirectional communication (recording motor commands and sensing sensory signals) with future neural prostheses.

ADVANTAGES
  • Easier targeting of remotely spaced nerves or muscle tissues.
  • Ability to adjust intra-electrode distances at the time of surgical implantation.
  • Eliminates entanglement of individual electrodes and connecting elements.
  • Allows for better management of electrode leads and active electrode contacts during surgical procedure.
CONTACT

For additional information about this technology opportunity, please contact Elizabeth Garami at egarami@fiu.edu or by phone at 305-348-0008 and ask about record IP 1223.