Cortisol Detector

TECHNOLOGY OPPORTUNITY

Florida International University (FIU) is seeking a business partner to develop and commercialize a new disposable electrochemical biosensor for the detection of biomolecules at point-of-care (POC) applications at reduced costs. The device is portable and measures the concentration of an analyte in fluid. The device has been tested for the detection of cortisol in biological fluids.

POC systems that can quantify critical physiological parameters can enable better diagnostics and better treatment strategies. Currently available techniques do not lend themselves well to miniaturized automated systems for application at POC. Many of the current sensing systems cannot be applied at POC due to constraints of portability, cost, analysis time, and requirement of highly skilled personnel to operate the systems.

The technology uses disposable biosensors to detect an analyte on an electrochemical biosensing platform, which is based on binding agent-analyte interaction that provides the specific and selective detection of a target analyte.

The binding agent of the electrochemical sensor can be a binding protein, an antibody, or an aptamer, and the analyte can be a biomolecule, for example a hormone, a protein, a polysaccharide, a lipid, a polynucleotide, or a metabolite, and the fluid can be a biofluid. The technology can also be used for detecting the presence of a disease, or assessing the likelihood of development of the disease associated with abnormal levels of a biomolecule.

APPLICATIONS
  • Portable device for point of care applications for quantitative antibody based assays.
  • Help in detection of diseases or assessing the likelihood of developing Addison’s disease, Cushing’s syndrome, adrenal insufficiencies, psychological stress or posttraumatic stress disorder.
ADVANTAGES
  • Highly sensitive.
  • Applicable to the testing of different bio fluids.
  • Portable, miniaturized, and automated system to use at point of care.
  • Low cost, rapid analysis time, and requires small sample volume.
CONTACT

For additional information about this technology opportunity, please contact Shantanu Balkundi at sbalkund@fiu.edu or by phone at 305-348-8061 and ask about record IP 1401.